If you uninstall the Generations program using Control Panel, Add/Remove programs you will not lose your family file. But as always, it is essential to create and keep frequent backups, File menu, Save A Copy, and save copies in multiple locations.
When you make backups onto CDs, please be aware that it is impossible to open those backups directly from the CD. You have to copy the backup from the CD to your hard disk before you can open it.
I think you need to determine if the problem is your computer or your family file. To do that, temporarily install Generations on another computer for testing purposes, copy your .uds family file to that computer hard disk, and see if it works or not.