My wife is Blake, and her father is from St. Elizabeth. I have recently learned that she had a great uncle by the name of Amos Blake. I am wondering if it's the same one you mentioned in your post. If so, Amos would have had a brother by the name of Eustace Blake, who was my wife's paternal grandfather.
My wife also has connections to the Mullings family by way of the Blairs.
All of this family is from the area south of Santa Cruz (Folly, Russells, etc), Saint Elizabeth.