Rebecca...The Barbour Co, AL, clinches it.Stephen and John Wesley and sister have to be some relationship to my Hugheses---perhaps Stephen and E D Hughs were brothers?Have you checked if Stephen served in Civil War?Did you say he was born in S.C. or GA?
My great-great-grandfather was E D Hughs (actually "Hughes" but mis-spelled when he joined AL 60th regiment CSA in 1862--formed out of men in Barbour Co, AL).
E.D. married Mary Phillips and had at least one child, Louis David, b. 1852, who married Iantha Clark in Barbour Co, AL, in 1871.Together L. David & Ianta had 12 children:10 boys and 2 girls---one of whom was my grandfather.The children were born between 1872-1895:Eli, James, John, Henry, Wash, Harvy, Doc Edgar (MY GRANDFATHER), Oscar, Mae, Adolphus, and Velma.The ENTIRE clan moved to Shelby Co, TX, about 1900, my best guess.