The plot thickens! John D. Johnson was practically a next door neighbor of Alexander and Susan Lowe. Depending on where the Johnson house actually stood, they either lived one or two houses away. Their land was as close as 1/4 mile apart. This land was patented on 11/20/1839.
John Franklin Lowe, depending on the location of the houses, could have lived as much as two and half miles from Mr. Johnson, perhaps more by road.
As close as your Lowe line's land lay was 6 miles away, as far as patented government land.
Mr. James Donnelly was the next door neighbor of John Franklin Lowe. Looks like it was indeed probably John Franklin Lowe that was murdered! Wow. Murder mystery solved...perhaps.
To answer your question, no, I live in Birmingham, Ala. I grew up in Pickens Co., though. I still visit fairly often.