Re: San Francisco birth records 1852?
1910 census, White Bird, Idaho, Idaho
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Thomas R Mayo 57 CA f FR CAN m SPA
Alice L Mayo 56
Alice L Mayo 18
1895 MN census
Thomas R. Mayo42 CA
Alice L.41 IN
Nina Candace8 MT
Although this is just a theory, Nina is a Spanish name, and I strongly suspect that was his mother's name.
Have you tried looking in Canada? He disappears until the 1895 MN census, and with a father from Canada, it seems as if he was probably raised there.