I finally located a document that is very important for the Lowe history:
I now know that my grandfather George Washington Lowe, born in WI and his father David H Lowe born in Jefferson County Ohio (Not documented yet but know this is true), and his father William Lowe who was married to Mary Sanderlin (now the good part - was married in Jefferson County Ohio:
Page 120 dated November 21st, 1828 left side page, second entry.
Jefferson County State of Ohio etc.
This is to certify that I have solemnized the marriage contract between William Low and Mary Sanderlin according to law this 9th of Nov 1828