Hi Clay, In the 1914 R. L. Polk Directory for Colorado Springs and Colorado City a Jeffryes, Clyde C. Mrs., seamstress, rents 155 Osage Ave., Manitou Jeffreyes, Ida, 155 Osage Ave., Manitou
I don't think Clara/Clyde and Isa left Manitou with Frederick.
I couldn't find death info for Frederick or Julia. There is a volunteer in Stanislaus Co at Random Acts Genealogical Kindness. Go to raogk.org Choose California Click on S Scroll down to Stanislaus Co. and choose Colleen.
I do think the Clyde and Joan in Wichita in 1920 are Frederick's former wife and child. Clyde lists herself as widow which was often done when a divorce was involved.
I'd post your message in Sedgewick Co., Kansas and ask for more info about Clyde/Clara and Isa/Joan. Successful Searching!