I have found lots of clues for you to help in your search.
In the 1900 Census for Bay City, Michigan, at 2505 Garfield:
Mary Sheldon, age 71, born Aug. 1828, in New York, Parents born (illegible), widow
Emily Dullet, daughter, born Michigan July 1870, age 29, both parents born NY,married 10 years (i.e. not widowed), 4 kids, 2 still living.
Ione Dullet, age 5, born Michigan, parents born Michigan.
Velma Dullet, age 3, born Michigan, parents born Michigan.
Susan Hopkins, boarder, single, 43, born New York
1910 Census for Bay City, 2505 Garfield:
Emily Drullette, age 39, born Michigan, parents born NY, widow, 4 kids, 2 living
Her two daughter's names are difficult to read, but they could easily be Ione and Velma. Ione is 14, Velma is 13, both were born in Michigan, their father was born in Canada, and their mother was born in Michigan.
Susan Hopkins, age 53, single, servant, born NY
Note: Living at 2509 Garfield is the family of William A. Shelden, age 53. He and Emma had been married 26 years and had an adopted son, Charley, age 16.
1920 Census for Bay City, 423 Nehobish:
Emily Drullett, age 47, widowed
Susie Hopkins, single, housekeeper, age 60
Then from the Bay City City Directories noted:
1890 - 1891: Samuel Drullett, laborer Bay City Box Factory
1899: Mrs. Emily C. Drullett, boards 2505 Garfield
1902- 1903: Mrs. Emily Drulett, boards 2505 Garfield
1906: Mrs. Emily C. Drulett, boards 2505 Garfield
Mary A. Shelden (widow Ancel) resides 2505 Garfield
1913: Emily C. Drulett (wid Samuel)
Ione Drullett bds. Mrs. Emily C. Drullett
Velma Drullett bds. Mrs. Emily C. Drullett
1913-1914: Emily C. Drullett (wid Samuel)res. 2505 Garfield
Ione Drullett, student, boards 2505 Garfield
1916 - 1917: Emily C. Drullett (wid. Samuel)Coach clnr P M RR, res. 127 McEwan
Ione Drullett, knitter World's Star Knitting Co bds 127 McEwan
Velma Drullett, knitter World's Star Knitting Co bds 127 mcEwan
It looks to me like the son, Lawrence may not have lived very long, as he is not in the 1900 census. In both 1900 and 1910 Emily claims to have had 4 children with two surviving. So, it looks like any descendants would have been through the two daughters.
It looks like Samuel was still alive in 1900, for the census when Emily is not shown as a widow. Furthermore, in the City Directory entries of 1899, 1902 and 1906 Emily is not listed as a widow.