Kim, Prior to the formation of Pike County in 1815 that area was part of the Virginia Military District. Most of these lands were bought and settled by farmers as was the case for my ancestors. The oldest brother of my 3g grandfather settled in the area prior to 1800 and after Pike County was formed served 18 years as a county commissioner. After their father's death in 1802 my 3g grandfather and another brother also relocated there and started prosperous farms.
Another of my family lines left PA, lived one generation in what is now WV then moved to southern OH. They were also farmers
Both these lines have descendants still living in OH but also bothe had members who moved into Eastern IN still searching for better and larger farms to accomodate their growing families.