Don't have any medical history but here's a little of the tree.
1930 Travis Co. TX Census Austin P70 511 &1/2 West 6th Cain Hugh head m w 46 WD AL AL AL Electrician City " Irene dau f w 21 sgl TX AL TX " Lois dau f w 20 sgl TX AL TX " Leroy son m w 18 sgl TX Al TX " Frances dau f w 16 sgl TX AL TX
1920 Travis Co., TX Census Austin City 5 WD P16 Cain Hugh head m w 36 M AL AL AL Steel Worker? ? " Bonnie wife f w 30 M TX TX TX " Irine dau f w 11 sgl TX " Loise dau f w 10 sgl TX " LeeRoy son m w 6 sgl TX " ?ulia M dau f w 5 sgl TX
1910 Travis co., TX Census 2 J-PCT P50 Cain Hugh head m w 27 M1 2 AL AL AL Laborer Farm " Bonnie wife f w 21 M1 2 2kids 2living TX TN TN " Irene dau f w 2 sgl TX " Lois dau f w 3/12 sgl TX Several men same page might be father of Bonnie Glenn Will T 43, Vincent John L 50 TN
This might be Frances rom Texas Birth Indexes Frances Marcyle Cain & James Gerard Lee had: Lee Nancy Marcyle 1949 Travis County.
I'll see if I can find Hugh's family.He not there in the 1900 census, maybe back in Alabama.