I do not think there is a connection. Eleanor Bryan was the sister of Rebecca Bryan Boone. She met and married Ephraim Adams in what is now Davies Co NC -- both lived at / near the so-called Bryan Settlement at the bend of the Yadkin. The family left NC before 1800. Although there is no record of Ephraim's death, he probably died in Kentucky sometime between 1797 and 1800. He and his children are named in the will of his father, Daniel Adams of Pulaski Co KY and his father-in-law, Joseph Bryan. Eleanor Bryan Adams subsequently married Josiah Boone and the family moved to Sullivan Co IN.