The James (Thompson) Atkins you referred to who married Margaret Patterson in Wythe Co., VA, is very well documented in Robertson and Montgomery Co., TN.
James Thompson Atkins was the son of Joseph Atkins and Jane Thompson Atkins of Wythe Co., VA.
Source:"Tennessee Settlers and Their Descendants" The 22 Oct 1814 will of Joseph Atkins which was proved on 9 Jan 1816 in Wythe Co., VA mentions slaves he gave to family members as follows:
Wife Jaine Atkins-Cloa, Dills, Poll, Malvina, Burrell Son Thompson Atkins -Moses U. Harvy Son Nathaniel Atkins -Will and Primis Daughter Polly Thompson -Murry Nanny and Rachel
http://freepages.genealogy.rootsweb.com/~nightshade/Folks_Families.html#261http://freepages.genealogy.rootsweb.com/~nightshade/Folks_Families.html#261 JANE CULTON ATKINS Jane Atkins was born June 27, 1805 in Robertson County, TN, the daughter of James Thompson and Margaret Patterson Atkins. Both parents were born in Wythe County, Virginia. Jane married James Hamlett on August 13, 1823 in Robertson County. She died October 4,1824 in Port Royal, Montgomery County, Tennessee.