Sorry if I confused you. I didn't mean to! I descend from James Scott Agnew (b. 1742) who is the son of James Agnew and Rebecca Scott. He is my 5th great grandfather. Your David Lester Agnew (b. 1743, who married Mary Irwin (Erwin), is his brother. James Scott Agnew m. Mary Ramsey in 1768. They had at least 9 children that I know of. I descend from their oldest son James Ramsey Agnew born in 1769.
James Agnew (1711) m. Rebecca Scott James Scott Agnew (1742) m. Mary Ramsey James Ramsey Agnew (1769) m. Elizabeth Steele Finley David Agnew (1811) m Rebecca Sample Nathaniel Sample Agnew (1845) m. Mary Ritchie John Patterson Agnew (1879) m. Roberta Anne Blanchard James Blanchard Agnew (1915) m. Virginia Jeanette Kerwin