This is not my line.Could it make sense that your Mary Patterson Blake died and Lewis remarried?Or have you been able to rule out the other Lewis Blake marriages?Not sure if any of these notes will help, or just add confusion ....
Lewis A Blake md Mary Patterson 28 July 1858 Gallia Co OH
1860 Gallia Co OHSpringfield Twp #blank/illegibleimage 00006(you might want to check image to see if you can make this out) Blake, illegible 22 OH, male illegible 21, birthplace blank, female
(I also noted there was an Anderson Blake in Cheshire Twp 1860, with no age; might check that one, too)
Lewis Blake md Ann Eliza Susan Wallace 31 Jan 1862 Gallia Co OH Lewis Blake md Rebecca Jane Davis 5 Dec 1866 Gallia Co OH
1880 online Beaver, Hamilton Co NE pg 315d Luis BLAKESelfMMaleW39VAFarmerVAVA Rebecca J. BLAKEWifeMFemaleW30OHKeeping HouseININ
1900 Rhea Co TNCivil Districts 11, 13 Blake, Louis A March 1837 WVa VA VA md36y Rebekah OH Sept 1843 OH Germany IN md 36y 1ch/1 living Charles A Jan 1880 Nebraska WVa OH, son Julian, Charles Feb 1873 KS Prady, John Feb 1877 TN Myers, Thomas J June 1874 TN Martin, William S Jan 1878 TN
1910 Bradley Co TN Civil District 3 Ablake, Lewis 74 VA VA VA md Rebecca J 68 OH VA VA md Jennie 7 IN VA VA step-daughter
1910 Bradley Co TN, Cleveland Ward 2 Blake, Charles A 32 Nebraska Germany Germany md Bessie 20 TN TN TN wife Edith R 3 dau TN NE TN Lela R 2 dau TN NE TN Walker, Nellie A 19 TN TN TN divorced Carl F M 2months TN TN TN
There is a TN death record for Rebecca Jane Blake d 14 Mar 1915 Cleveland, Bradley Co TN, female, married, white, age 69, b OH; parents: Thomas Davis b East VA & Rebecca Brown b VA; bd Cleveland TN
Note:There was an Arius L Blake, s/o Samuel & Nancy in 1850 Springfield, Gallia Co OH, but some info shows he died during the Civil War in 1863.