I'm not related to the Boughtons. My grandmother, a packrat, was raised by Andrew Perrin Potter and his wife. Potter lived in Pipestone from 1846-1851 and apparently became good friends with Orlando Boughton during that period.
Potter emigrated from Michigan to California in 1853. From thecomments made in Boughton's letters to Potter, I got the impression that Boughton might have made the journey at the same time. The wagon master was John Clifton, and the group first went to Oregon before coming to California. Boughton mentioned Clifton by name.
Boughton made at least one more trip to California around 1876 and stayed for a time with Potter. Boughton mentioned his interest in the San Jose area of California in his 1877 letter.
An online transctiption of Gavilan HIlls Cemetery in Gilroy, CA, includes an O.S. Boughton with no dates, also no wife. I tried to find a death date for Boughton in the online death indices for California to no avail.
Potter was 17-22 during the five years he lived in Pipestone, and died in 1907. My impression is that Potter might have worked for Boughton in Pipestone.
At any rate, I have very little direct information on Boughton other than what I've already shared. Sorry I couldn't be of more assistance. Anita