Last night we figured out the connection between Jared Wade (my mother-in-law's great-great-great grandfather) and Anne Dudley Bradstreet as follows:
Gov. Simon Bradstreet and Anne Dudley | Mercy Bradstreet | Jonathan Wade, 5 Mar 1682 or 1683 to ca. 1710 (m. Mary) | Nathan Wade, 22 Feb. 1705 or 1706(m. Deborah Hawkins) | Gideon Wade, 3 Apr 1746 to 10 July 1767 (m. Phebe Hopkins) | Jared Wade, 25 Sep 1793 to 1882 or 83 (m. Tryphena Seaman) | Sarah Jane Wade, 1 Nov 1824 to 1 Nov 1903 (m. Myron Nelson Mead)
That should be far enough down to give an idea of the connections.