Thanks for the reply. I do not think your Elizabeth Bramlett is my Elizabeth Bramlett who married Louis Lee Waldrep and born 1852 died 1926. I am told her parents were Richard Bramlett and Victoria McGuirs but have not found a census on them yet. Do they ring a bell with you. I have no other information on the Bramlett family. I would like to find out which parent passed this bad gene. Any help on that would be greatly appreciated. There has been a break through on medication for this disorder and I would like to share this info with anyone affected.