William Wade Brewer b.abt 1850 Mo.

We are looking for any information on any Brewer's from Mo. . My husbands g-father was William Wade Brewer. He could have had a brother named John. He was married in Mo., but we do not know to who.He and his wife had two children ,a daughter Vassie and a son, I think the sons name was Willie. After his wife died, he removed to Claiborne Co. Ms. There he married Sarah Frances Barrett. They had six children, William Wade Jr., George, Lucy Jane, Tempie Caroline, and twins (one of which died shortly after birth) and Willie only lived a few days. Any help would be appreciated.

Thanks,