Strother Bruffey had several children. I've seen quite a few postings by his descendants. His father George was one of several Bruffeys in the hill country of VA. I don't know more.(My branch was further west in what's now WVa. I'd look at the LDS web site and at postings at familyhistory.com where there's Bruffey and Bruffy sites.Spelled sometimes as "Bruffie" too.You might find your grandmother's parents and then work back to Strother or one of his brothers or cousins.