Since my previous posting, I have learned considerably more about the Calhoon line. There are numerous lineages for this family on worldconnect.com. I found that James Calhoon (b.1796 in Iredel Co., NC) married Elizabeth Stephens (b.1807 in VA) on 13Oct1831 in Gallia Co., Ohio.
James' parents were Robert Calhoon (b.1765 in Gilford Co., NC) and Amelia Mounder (b.1766). They were married in 1785 in NC and had at least 9 children.
Robert's parents were James Irvin Calhoon (b.Jan1795 in Orange Co., NC) and Jean or Janet Johnston. They were married abt 1759. They had 14 children, including son Samuel (3rd child) born abt 1764 and died in Georgia. This is possibly your wife's ancestor Samuel.
James Irvin Calhoon's parents were Alexander Cahoon (b.1700 in Nansemond Co., VA. and Easter. They had 8 children including a son Samuel.
Alexander Calhoon's parents were Samel Cahoon (b.abt 1663 on Block Island (in present day Rhode Island) and Mary Hunter. They were married abt 1698 on Block Island. They had 6 children including a son Samuel II (b.abt 1698).
Samuel Cahoon's parents were William Cahoon (b.abt 1633 in Tullichewan, Dumbartonshire, Scotland) and Deliverance Peck (b.abt 1637 on Block Island). William and Deliverance were married 26Jun1662 and had 7 children.
The ancestry of William is in dispute. Many researchers assign him to one of two prominent lords in Scotland. Experts tell me there is no evidence of such a connection. Colquhoun was a clan name and fatherhood should not be attributed to the lord of the clan. William has a very exciting history.
You can read more about the Cahoons in "Famous and Infamous Cahoons" Vol. 1 by Deborah A. Cahoon Didick. They had at least one large reunion of William Cahoon descendents. To buy the book, contact Deborah Didick email@example.com .