Hi! I live in the county of Suwannee in FL. I do not know of a town by the name though... however, there is a Suwanee, GA and Sewanee, TN. I am not familiar with those names as mentioned together. I do have a James in my line but he went to TX around the turn of the 20th century sometime where he died around 1925 around El Paso, TX.
That is the only information I have to offer regarding the subject... Sorry!