It would interesting to compare information on your father's side of the family as my father was Ernest Edward CLOE.He was born 2 August 1873 in Clay Township, Hamilton County, Indiana and died 26 March 1945 in Noblesville, Hamilton County, Indiana.His father, Abraham W. (Henry) CLOW was born 23 April 1850 in Marion County, Indiana and died 11 April 1921 in Noblesville, Hamilton County, Indiana.Grandfather was from a large family and was orphaned when his mother died in 1863 (his father - Willam J. CLOW - died 25 December 1854).
Of the seven children of William James CLOW and Elisabeth Rebecca RINGER, I have only been able to track two of the boys. Louisa, Susan U., Rebecca E., Sarah J. and William J. (born just after his father's death) have all but vanished.
In answer to your question of the Cloe's of Illinois being related to the Cloe's of Virginia.The answer is possibly.James CLOW and Elizabeth BIRDWELL had seven sons and four daughters. After the death of James in Virginia, Elizabeth moved the family to Kentucky.From there they scattered to Indiana and Illinois.One of the seven sons was William Howard CLOW who was married five times and resided in Indiana, Illinois (I believe) and in Benton, Arkansas.At the same time I have information on a different line (three brothers) that also came from Scotland but fifty some years later and settled in the New England States until after the war of 1812 when one brother moved to Kentucky, then to Indiana, then to Illinois and finally back to Indiana.Then you have the Scottish CLOW's that went to Canada and then into the U.S.
The database I have on the CLOE/CLOW has several disconnected lines but as I have found out in the past, new information on one individual suddenly connect two previously non-related CLOE/CLOW lines.
Any information you wish to share would be entered in the CLOE/CLOE database and I will share with you what I have compiled from other individuals.