I am starting to agree with you that Anna Marie Will was not married to Alexander. I assumed she died before he married Anna Mack. This can't be the case if she registered to emigrate to America. When one genealogy says that Alexander left Schriesheim with Anna Marie Will, perhaps they were fellow passengers, and not husband and wife.
One statement you made intrigues me. "...and per the passenger records (Anna Marie) arrived in Philadelphia in 1727." I have found no records for the William and Sarah that list the women on board. Do you have such a thing?
This is all totally unimportant in the global scheme of life, but fascinating stuff!