I have little information on this James Drennen.I have that he was born in or about 1817 in what is now Jefferson County, Missouri.I have three wives for him: Sevill Wideman, Catherine Moredock and Sarah Cain.He was the son Of William Drennen and Elizabeth (probably Leffler).William Drennen was first married to Ann Hildebrand, and had the following children with her: Jonathan (1797 KY), Sarah (1800 MO), Jane (abt. 1802 MO) and William Austin (1803 MO).William and Elizabeth had the following children: Elizabeth (bet. 1810-1820 MO), James (abt. 1817 MO) and Anna (abt. 1822 MO). I have much more information about William Drennen, and some generations before him. I have 5 other James Drennen's in my database, but this is the closest one to the dates you mentioned.