According to the Genealogical Dictionary of Maine and New Hampshire, page 245, William and Elizabeth had several children: "Besides ch. Jane, Samuel and John, to whom he deeded lands, he presum. had others: Jane (or Joan), m. by 1671 Tho. Holmes. Elizabeth, m. 1st Isaac Botts; 2d, July 1679, Moses Spencer, whose s. Moses named his first ch. Freethy. James, town gr. 1680. Samuel, in 1683 with br. john recd. deed of homestead."
I am descended from Thomas Holmes and Jane/Joan/Joanna who are 9th great-grand parents on my father's side.