I have a Penelope Hance who married Jacob Jacobs in 1843. Penelope was about the age of 19 or 20 when she married Jacob. Their marriage was recorded in Jefferson County, TN. I also know that the Jacobs' land was located on the Nolichucky River in Jefferson County which borders Cocke County. Penelope may have been from Cocke County.
I also have reason to believe that Penelope's maiden name was Franklin. Thus, her birth name could have been Penelope Hance Franklin or Penelope Franklin Hance. She could also have been married once already to a Mr. Hance before her marriage in 1843 to Jacob Jacobs.
Do you show a Penelope in any of your family data from East Tennessee?