I'm sorry I wasn't clear on my posting about Andrew Henninger. One of Andrew's living decendents contacted me with some of the information I referred to in my post. You are correct John's son was Andrew, I have no information that there was any other Andrew's in my tree at all.
It turns out that John J. and Catherine Singley had 12 boys starting 1823 thru 1847, instead of the original information I received from my father stating there were only five.
My line begins with the son named Isaac, a brother to Andrew. I still live in PA. Andrew is the only other brother of the twelve that I have found a living connection with so far.