The Ephraim you are seeking was an uncle to my g grandfather. He was the son of John and Susanna (Gustler) Isenberg. 1819-1906 m 1857 to Margaret McCarty 1836-1925. Sphraim was a stone mason. He and Margaret resided at Dixon, Il which is in Whiteside Co or Lee Co. They had Six children:
Lydia Ann 1857-1936 m 1883 to Frederick William Fox 1854-1904 Frederick was a Carpenter and Farm Worker. They resided in Dixon. They had five children.
Ellen Louise Isenberg 1859-1938 m John Edward Lenox 1856-1915. John was a farmer and road builder. They lived at Gap Grove, Lee co, IL Four children
Louise Isenberg 1861-1932 m 1. 1883 to Emery Frazier 1862-1895 m 2 Fred Randall. They resided in Dixon, Il. Two children.
Mary Catherine Isenberg 1863-1964 m 1888 to Lewis Augustus Beatty 1858-1934. They were farmers in Dixon, IL. five children
William Isenberg b 1867 m 1889 to Anna Kinney. Resided at Amboy, IL They had three Children
Edward 1873-1949 Edward resided at Grand Detour, IL Died without issue
This information came from An updated history and genealogical record of th Isenberg Family written by Lillian Isenberg Bahney. The book is available from the Ursinus College; Collegeville, PA for $39.00.It is over 1,000 pages and well worth the money. Let me know if I can be of further help. Betty