Here is the specific information I have for Francis:
Francis Kuehly b. 11 Apr 1791 bp. 22 Oct 1791, 1st Ref Ch. Phila source: IGI (batch 7825603)
Baptism records for Esther, Samuel, Elizabeth, Morton Brealsford are on the same source. (You probably already know this, but I just recently learned the trick of doing an IGI search on a batch number and leaving the name blank.)
The only other thing I have is that a shipping ad in the paper in 6/21/1803 says "Matthias Keeley and Son, No 3 North Water St." I've been thinking that the son who joined the business was Samuel, who would have been almost 20, but maybe William or Horatio-Nelson was older.