I have just been following the KEEN family in York County, VA, from 1688-1790's.
I find a John KEEN and wife Mary starting in Deeds, Orders, and Wills in 1688. He seems to have died in 1692 and left his estate to his wife Mary, daughters, Elizabeth, Mary, and Ann, and three sons below 21 years of age, John, Charles, and Jeremiah.
I find what appears to be John KEEN, Jr., from 1704, with his wife Obediance, selling land, down through 1755.
I then have a William KEEN who I can't tie to the above KEENs who shows up in 1758 as a witness and goes through his death about 1792.
Happy to share any of the specifics if you have any interest.