All I recall of Isabella Walkington is that she married Boyer Killip. It appears that she came from Castletown in the Isle of Man and may have met Boyer there before they emigrated.
Isabella may have owned a hotel in Douglas before she emigrated - I have no knowledge of that, but if you visit Frances Coakley's site - there are listings from the various directories during the 19th century that may enlighten you. http://www.isle-of-man.com/manxnotebook/index.htmhttp://www.isle-of-man.com/manxnotebook/index.htm
If I find out anything else about Isabella I will e-mail you directly.