Elizabeth, if your still out there, I'd be very interested to talk to you re: Isetta.
She was the niece of my gg grandfather George Thomas Langhorne, brother of her father William Beverly Langhorne.
I've got a good bit of information and also know that both her father and uncle(my gg grandfather) moved both families out to Newport Kentucky for a few years it appears.Of my lines George's children, 2 children in the middle were born in Newport, KY, the rest being born in Phila.Isetta too had siblings who were born in Ky, yet others before and after were from Phila.
Also, in case you did not know, Isetta's father was born in Virginia and she is descendended from the Virginia Langhornes going back to the first immigrant in Williamsburg in 1670.
Please post a response or email me directly at firstname.lastname@example.org