Hi, you may already have this information, which I got from several family trees on Ancestry.com. My direct descendant is Juan Lujan III, not Maria, but I was unable to find any information on whom she married or the names of her children.
Juan Lujan II, born 1602, is supposedly Mestizo, with his Canary Islands-born father Juan Lujan and an Indios wife, Francisca Jimenez. Juan Lujan II married Maria Sosa and had three children that I know of: Juan Lujan III Miguel Maria
Please let me know if you need any more information or have some to swap.