Maybe I can help a little with info on sons of Valentine Mayo who married Ann Patterson.My ancestor is his son Valentine who married Martha Hughes and settled in Monroe County, TN.
As far as James, the only information I have is that he was witness to an event in Blount Co., TN in 1803, involving his brother Valentine but then he disappears from the records as far as I have been able to tell.
I have Thomas Mayo as being born 1765 in Virginia. He moved to Campbell County, TN and later to Missouri. He married Mary Blair. His clan were some of the first settlers in Randolph County, MO.
Following is from "History of Randolph County Missouri":Allen Mayo was born in Virginia. July 14, 1802. His parents were Thomas and Mary (Blair) Mayo. Thomas Mayo served in the Revolu- tionary War under Washington. About 1805, he removed from Vir- ginia to Tennessee and was engaged in farming in Campbell County until 1817 when he came to Missouri. In the spring of 1818 he came to Ran- dolph County and here built a log cabin and cleared a piece of land and spent the remainder of his days in this county.
Allen Mayo came to Randolph County with his parents and they were practically the first settlers in this section. Wild game at that time was plentiful and Allen Mayo, at one time killed three deer before breakfast. Wild hogs were commonly found in the woods and it is related that he killed twelve wild hogs in one day. He was a real frontiersman and was familiar with all the buffalo trails and every detail and condition of this country in the pioneer days, for a radius of miles around. He dis- covered Randolph Springs, having followed a bualffo trail to that point and frequently shot deer in that vicinity and later salt was manufactured there. He died Feb. 16, 1894. His wife, who bore the maiden name of Martha Finnell, was a daughter of Charles and Lucy Finnell who were also pioneer settlers of Randolph County and came from Garrard County, Ky., where Mrs. Mayo was born June 28, 1804. She died July 5, 1890.
I dont see where any of these son's descendants moved to Indiana.