I think you have inadvertently confused Jeremiah b. 1698 in VA and married to Grace followed by Tabitha Edmonds with his son Jeremiah b. 1728 who was also married to a Tabitha whose last name was Howell. They also had a son they named Jeremiah b. abt 1748. It appears to me that all three of these were born in Virginia.
Joshua, son of the first Jeremiah, and Martha Patty had a son Jeremiah b. 1752, Anson Co, NC and d 1823 in Pulaski Co, KY. He married Elizabeth Gilliland and they had children including Isaac b. abt 1802 in Pulaski Co, KY where they had moved in the late 1700s. Isaac was my gggrandfather who had four wives and 22 children.