Tiffany and Anne Nettleton seem to be dead ends for now. Northfield on the Genesee p 188 states that they are brother and sister but we don't know about their origins. Having failed to trace them and with an established genetic link with a well documented branch of the Nettletons, I suppose the next step would be to look for offspring of that brahch that "disappeared." I think that some of the family must have migrated to NY and become "lost." My research skills are very limited but I aim to try.