Could either of these be your Melinda Nickless?You didn't mention any approx date of birth, or specific location, so hope this helps.Or, are you looking for her after she left MO?
In the1870 census there's a Melinda Nichols age 8 years in Central twp., Franklin Co., MO.
Jesse Nichols age 38 born TN Farmer is head of HH 10/10. (Wife?) Thankful age 37 born NC (Son?) John age 14 born MO (Dau?) Melinda age 8 born MO (Dau?) Mary age 4 born MO (Son?) James age 1 born MO -----------------
In 1880 there is a Melinda Nichols in ED 12, Boone Co., MO:
Head Wm. A. Nichols 53 Wife: Elizabeth E.37 Son:Phi G. 15 Dau:Iola A.14 Son:Curtly C.9 Dau:Melinda E.7 Son:Felix A.4