I have some information given to me by Camille Franklin Norfolk of Yerrington Nevada, I am sure she would want me to share what I had, although she would probably also want me to mention that some of the information came from a lady called Ethel Scleiffer who was a genealogist working on her own line descended from Isaac.
My understanding is that Isaac A. Norfolk was born 20.3.1790 and was the Second son of Thomas Norfolk Jr - He Married Married (1) Unknown Abt. 1809 and 2) Elizabeth M. Lawrence November 24, 1819 and their son, from Marriage (1) was also called Isaac and was born in 1810 in Calvert Co.Md he died before 1898, Sarah Anne Norfolk being his daughter born around 1830?.
I have the entire line from there back to Thomas Norfolk born in (My home Town) Otley, Yorkshire England, Descendants of Thomas Norfolk b.Thomas Norfolk third son of William bap. Otley 6.4.1640, William his father being our common Ancestor.
All the information I have is on XL Spreadsaheets. Please e-mail me for further info - firstname.lastname@example.org