In the book, DUTCH HOUSES IN THE HUDSON VALLEY BEFORE1776by Helen Wilkenson Reynolds(c. 1929; reprint 1965), there is mention of the NOXON family. "The house now known as 81 Market Street, Poughkeepsie, was built in 1741 by Bartholomew NOXON." The builder Bartholomew was born 1703 and died 1785.He was the son of Thomas NOXON, a Scotchman, who settled before 1700 in Ulster County and in later years removed to New York City to serve as headmaster of Trinity School.(Trinity School maybe the same Trinity-Pawling School now of Pawling, NY???).From 1731-1754 one sees Bartholomew NOXON as a taxpayer in Poughkeepsie, NY after he probably removed from Ulster County.1754-1770 he was living in Beekman Patent, paying taxes there.1770 to his death he once again in Poughkeepsie.After his death in 1785, the house was inherited by his son, Dr. Robert NOXON (1750-1833) and he occupied until his death. He was a prominent early Dutchess County physician.Noxon Street was cut through the property after the doctor's death.(There is also a Noxon Road which goes from Rte 55 at Manchester Bridge through the town of LaGrange to Rte 55 in Unionvale, probably near former Beekman Patent properties)The Poughkeepsie house was built of stone with a roof of single slant.The date of erection is learned from a stone in the east wall marked E BN 1741 for Bartholomew and Elizabeth NOXON. In this book, is also mention of a daughter, Margaret who married in 1753, James Van Der Burgh.(1729-1794) She was his first wife. They lived in house northeast of Poughquag., Town of Beekman., Dutchess County.James Van Der Burgh served as a colonel of the 5th regm'tof Dutchess militia. In 1776 he represented the county in the Provincial Congress of New York.
I would say that your Bartholomew is the son of the one I have discussed and was a brother to the above-mentioned Dr. Robert and Margaret.I have attempted to give you highlights of what is mentioned in the book. Good luck with your search.