I found some information o help you....... Samuel B. Oberholtzer did have a sister Elizabeth, however shedied whenshe was less than one year old.And as far as I know, Joseph S. Oberholtzer did not have any sisters named Elizabeth. Joseph did have three sisters, Catharine, Susan, and Lydia. I have the married names for all three and none are Shuler. (I checked that assuming Elizabeth was maybe the middle name or the the names I had were the middle name??)
The fathers of Joseph (Jacob S.) and Samuel (Abraham S.) were brothers. I even checked other siblings of the fathers to see if a match could be made. Their sister Susanna had a daughter Elizabeth but Susanna was born in 1774 so I doubt she had Elizabeth at the age of 16? Although, it is a possibiity. They (the fathers) also had a sister Elizabeth, but she was only born in 1781.
I just can not figure out which Oberholtzer your Jacob married.However, I plugged the information into my tree hopin for a match down the road.