Thank you for this information !! I believe this could be the David I am looking for. This time line would fit the David of 1763 and his infant son, David. Because David of 1763 left South Carolina and settled in Alabama around 1850. The information that I have states that the son was married by then. Also this Enoch Grubbs could possibly connect to the Isaac Grubbs that I have in my line.
You have been most helpful, but I am sorry to say that I have not ran across any Lotts in my search. But I will certainly be on the watch for them and I will let you know if I come across any.