I wish I could give you a definite answer.I can tell you what I think.
I BELIEVE William who died around 1812, in Fairfield District, SC, was descended from a William Pannell who appeared in 1740's in Caroline Co., VA.In 1750 he died and his son William Pannell, Jr. administered his estate.His widow Pricilla was supposed to have done so, but refused.
I know, the age doesn't match up with the one most of us have given the SC William, but there is no way to tell from the census records how old he was.In 1800 he was over 45 which could have meant anything.
By 1764 there do not seem to have to have been any more Pannells in Caroline Co. The Thomas and Benjamin who appeared there at the same time seem to be the same men who showed up in Amherst Co. a few years later.
Aug 1740 in Caroline Co. there was a deed transaction involving William Pannel the wording of which proves he was a direct descendant of the original Thomas Pannell of Old Rappahannock Co., through his son Thomas the second.
Caroline Co. records are very scarce but some order books survived the Civil War.
I ruled out descendants of William Pannell who was the son of the original Thomas and brother of second Thomas.Except for one of his sons named George who sort of disappeared I don't believe there is any way we are descended from them.And I sure tried!They were so well documented.
As I stated at the first, this is my own belief and I hope no one will take it as fact without more proof than I have.I have seen too many rumors and I don't want to be the cause of another "urban legend."
The William Pannell whose estate was settled in 1810 Fairfield Co./District SC was William Jr. son of the William you asked about.I have not found a will or estate settlement for the older man, probably because he had sold off most or all of his property to men we assume were his sons and a possible son in law.
I would be happy for you to email me at Slprice6@aol.com if you want to.I would like to make that connection, too.