No, Ephraim's widow was Laura (Bingham) Draper Perrin, who is on the 1850 census in Granville.She was much younger than the person you found in Alleghany County.
Hannah (Draper) Perrin, Ephraim's first wife, would have been 75 in 1850, but she had already been dead for about 27 years as of that date.Hannah (Jones) Perrin, the second wife, was likewise deceased by around 1841.(I may have the exact date in my workbook.)
The Hannah, Emaline and Evaline Perrin you found must be must later emigrants from Connecticut.The Granville Perrins had left the Nutmeg State by about 1780, and all of Ephraim's children were born in New York.Others of the Hebron Perrins came to New York later on, but it should also be noted that descendants of John Perrin of Rehoboth, Mass. spilled over into Connecticut, so Emaline and Evaline could be of that branch.