I am a descendant of Opechancanough through Mary Sizemore. Though I do not have proof of this as of yet, just family history handed down by word of mouth. It was pretty exciting, to me, to see someone else post the name as I was starting to lose all hope of any confirmation of this.
The story that was handed down to me was as follows:
Chief Opechancanough had brought back a woman from his attack on Jamestown in 1622. Her name was Mary Sizemore. They had a child named Goldenhawk Sizemore. Goldenhawk left the Powhatan's to live in the "white" world. As he was traveling south, he met a woman named Agnes "Aggie" Cornett Shephard, who was supposedly half Cherokee. Many of the Sizemore's are decended from this union as one of Goldenhawk's descendants was George All Sizemore, who had some 50+ children.
There is quite a bit of information on George All Sizemore, but so far I have found nothing showing a connection back to Opechancanough. I tried writing "littlewolf" back at his posted email address, but to no avail. If you, or anyone else reading this, has any information reguarding this or a contact email for "littlewolf", I would greatly appreciate it.