Gus, According to the book:The Descendants fo Robert and John Poage, compiled by Woodworth, 1954, James Anderson who married (1797) (Nancy) Ann Shirkey (the daughter of James and Elizabeth (Poage) Shirkey / Sharkey was the son of James Anderson and his wife Maggie.
James II and Ann (Shirkey) Anderson had the following children:
James n.m., d. ca 1840, Margaret m. Elijah Bolinger a child Henry Elizabeth m. William Armistead Williamson Amelia m. Thomas Paxton George m. 1st Mary Tucker ten children m. 2nd Mary Jane Lemon six children William m. Georgiana Backus five children Matthew m. Mary Ann McCluer seven children Ann m. __ Lane Sarah m. Jared Morton a son John n.m., d. prior to 1840
I don't know if any went to Nelson Co., VA.some lived in Eagle Rock, VA and Bessemer, VA.The children moved on to IN, IL and IA.
The Poage Book has some errors in my line but it has a vast amount of information.I don't own the book so I don't know what else it has on the Anderson Line, except what I have listed above.