I have two descendants of W VA Slayton families in my contact database. Their ancestors are from the "Northern" Slayton line, and they settled in Mason and Cabell cos W VA. Does this sound like your bunch?
Otherwise, a Daniel Slaton/Slayton & Mary (Polly Grant) settled in Pocahontas co W VA and produced a family that included men who chose opposite sides during the Late Unpleasantness. Please let me know which names you are looking for and we can network you in.