I believe Serena was the daughter of Solomon Stegall and Lucretia Arney. I have her b. 1839 and on the 1850 Fayette, IL census as "Cyrene" - a male - which threw me off for a long time. Solomon and Lucretia had several children, and they all lived in Fayette Co in the 1850s, and after that they seem to have left for Texas and Mississippi.
My connection is Serena's cousin, William, who was the son of Solomon's brother William. I *think* that William's parents died before 1850 and that William and his sister (?) lived with Solomon's family...but that's an ongoing search. I'll let you know if I find anything more.