The more I consider this, the more that I think about the Windsor, Berkshire aspect.We are talking about a lot of geography here regarding Sansone/Sension/St. John.
Yorkshire (at the latter part of the 1500's) which is north of Manchester, close to Scotland.
London (as the possible birthplace of Matthias, and later as a business owner there)
Windsor, Berkshire (which of course was the home of the Noble and Aristocratic Royal Families, but not the Saint Johns) as a reported place of marriage and birth place of some of their children (for which I cannot document any of that)
Where does that leave me? With a stiff scotch, neat.