From the book "Hopewell Friends History, 1734-1934, Frederick County, Virginia" is the following:
"Mark Thatcher, son of Jonathan and Hannah Thatscher of Berkeley County in the State of Virginia, and Hannah Thomas, daughter of Ezekiel and Rebecca Thomas, the latter deceased, of Frederick County and State aforesaid; 16th day of 4th month, 1823; at the Upper Ridge Meeting House." (This is a little north of Winchester).
Among the 47 witnesses were other Thackers - Jonathan, Hannah, Nancy, and Hannah, Jr.; also a Ruth Thomas.
I am not related to these people, and have no further information.