I, like you, are a descendant of Thomas Tyer, Lewis, James, John Ruffin, William Ruffin etc. The children of Thomas and Ann, I believe, are: Catherine, b. 1741//Lewis, b. 1743//John, b. 1744//Jesse, b. 1745//Thomas III, b. 1747//...but no Frederick. I will send to you via your E-mail address a sketch along the above lines.